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Finasteride For Male Pattern Baldness

Finasteride

Finasteride was initially formulated for Male Pattern Baldness (MPB). Further experimental studies suggest it may help reduce the risk of prostate cancer.

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Benign Prostatic Hyperplasia

Finasteride is used for the treatment of benign prostatic hyperplasia (BPH) (also known as enlarged prostate) at a dose of 5 mg once a day. It may take six months or more to see the full effects of finasteride. If the drug is discontinued, any therapeutic benefits will be reversed. Finasteride may improve the symptoms associated with BPH such as difficulty urinating, getting up during the night to urinate, hesitation at the start of urination, and decreased urinary flow.

Research Chemicals L.L.C. sells reputable Finasteride research chems.  The active ingredient of Propecia is Finasteride.

Liothyronine T3

Liothyronine aka T3 is marketed as Cytomel or Cynomel and often referred to just as T3. Liothyronine and other commercial drugs are synthetic versions of the body’s natural T3 hormones. Liothyronine T3 increases the basal metabolic rate (BMR), increases protein synthesis, and increases sensitivity to catecholamines. T3 hormones are essential to proper development and differentiation of all cells. They directly regulate dietary protein, fat, and carbohydrate metabolism, which determines in how dietary intake affects cellular energy production. In comparison to levothyroxine (T4), T3 has a faster onset and shorter half-life, possibly due to less plasma protein binding to thyroxine-binding globulin and transthyretin.t3 liothyronine

Clenbuterol HCL

Clenbuterol

There are several countries which have approved use of Clenbuterol,  because asthma patients use clen as bronchodilator and it is only allowed to be taken with prescriptions. Currently, Clenbuterol has been made popular by people who are using it “off-label” as a drug for weight loss; also these people are also using sympathomimetic amines like ephedrine. Clen which is mostly used to aid slimming has not been clinically tested.clenbuterol

Official Authorization

The U.S. Food and Drug Administration have not approved Clenbuterol to be an ingredient of the therapeutic drugs and the IOC athletes tested for this drug are banned. FDA has also banned people from giving of Clenbuterol to animals that will be consumed as food in U.S.

It used as a drug for enhancing performance

Clenbuterol is mainly used by the β2 sympathomimetic as a drug to enhance their performance. In 2010 at the Tour de France a cyclist from Spain called Alberto Contador was banned for a period of two years because he was tested for Clenbuterol and the results were positive. The title which he won after beating his opponent Andy Schelk by thirty nine seconds was stripped of from him and again in Gi d’Italia, the 2011 title was stripped of from him.

In the U.S trials which were held in July 2008, a swimmer named Jessica Hardy from America was tested for Clenbuterol and she tested positive. She was suspended for one year after she claimed that she took this drug without knowing it and that it was from taking supplements that were contaminated. In his plea deal, Kirk Radomski who was an employee of New York Clubhouse admitted that he distributed Clenbuterol to Major League Baseball players and these players included several former and current players.

Human Growth Hormone HGH Fragment

HGH Fragment 176-191

HGH Fragment has been noted to reduce abdominal fat.
- HGH Increases muscle mass.
- Increases IGF-1 levels, making this a peptide that burns fat and exhibits anabolic function.
- HGH Increases energy expenditure.
- HGH Improves lipid profiles and lipolytic activity.
- HGH Does not negatively impact blood glucose level, nor does cell proliferation occur, like Human Growth Hormone.

HGH

The (HGH fragment 176-191) is a stabilized analogue of the growth hormone-releasing factor (GRF) that induces growth hormone (GH) in a specific and physiological manner. To date studies suggest that (HGH fragment 176-191) has several beneficial features: it reduces abdominal fat (in particular visceral fat), without compromising glycemic control (blood glucose), it increases muscle mass and improves the lipid profile. These characteristics make it an ideal candidate for the treatment of excess abdominal fat, an important aspect of HIV-associated lipodystrophy.

At a dosage of 500mcg the (HGH fragment 176-191) was shown to increase lipolytic activity in adipose tissue. In other words this fragment potently burns body fat, especially stubborn adipose body fat, and it does so potently! Of significance, is that the fragment has no negative impact on insulin sensitivity, a stark contrast from its Human Growth Hormone counterpart.(Ng FM, Sun J,Sharma L, Libinaka R, Jiang WJ, and Gianello R 2000).

Not only does the (HGH fragment 176-191) not interfere with the body’s natural insulin regulation as Human Growth Hormone can, the (HGH fragment 176-191) does not result in cellular proliferation as (HGH)Human Growth Hormone does. The fragment is similar to (HGH)Human Growth Hormone, by the shared amino acid sequence, however, the (HGH fragment 176-191) won’t induce hyperglycemia or reduce insulin secretion. It does not compete for the hgh receptor and nor does it induce cell proliferation, unlike Human Growth Hormone. (Wu Z, Ng FM. 1993). Thusly, this is a very beneficial peptide in terms of burning fat, without unwanted and undesirable side effects. Of particular note is the fragments ability to increase IGF-1 levels which translate into the fragments ability to give collateral anti-aging and anabolic effects along with its ability to induce lipplytic (fat burning) activity.

In another study, the (HGH fragment 176-191) exhibits the ability to burn through adipose tissue by increasing lipolytic activity (the breakdown of fat), in the most stubborn body fat (adipose tissue) while increasing energy expenditure and glucose and fat oxidation in ob/ob mice treated with (HGH fragment 176-191). In addition, (HGH fragment 177-191) increased in vitro lipolytic activity and decreased lipogenic activity in isolated adipose tissue from obese rodents and humans.(Heffernan MA, Jiang WJ, Thorburn AW, Ng FM. 2000).

The (HGH fragment 176-191) exhibits the ability to burn through stubborn adipose tissue, while increasing energy expenditure, muscle mass, and fat oxidation. All studies have pointed to the fact that the fragment is an effective treatment for obesity and fat loss, and much safer than its Human Growth Hormone counterpart.

RESEARCH DOSAGE:
- 500mcg-2mg every day

T3 Online

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T3

Natural T3 is a regulator of the oxidative metabolism of energy producing substrates (food stored like fat, muscle, and glycogen) by the mitochondria. The mitochondria, are usually referred to as the “cells powerhouses” because they produce ATP.  Taking T3 greatly increases the uptake of nutrients into the mitochondria and also their rate at which they are burned for energy, by increasing the activities of the enzymes involved in the oxidative metabolic pathway. More fuel is needed to supplement this increased work rate. Therefore, as you can guess, taking supplemental Cytomel will increase your bodys energy demands. And if you are in a hypocaloric state, you will begin burning even fatter primarily due to an increase in ATP. This increased ATP causes an increase in overall metabolic activity.  This is exactly what we want, and is why we would be taking thyroid hormones like T3 in the first place. If you arent taking anabolic steroids with your Cytomel, however, your body may start to eat away muscle to provide energy for you to function. Remember mitochondria/ATP arent very picky, but they are very efficient.  This means that T3 will use whatever is on hand to generate energy for your body to continue functioning, fat, protein, glucose; it doesnt matter to ATP, as long as theres something to give them energy. Taking this drug will increase their need to find something to burn to create this energy.

T3 For Research

If you are looking to “buy T3” for research purposes you can do so at an online research chemicals store.

Advantages To Using T3 When Prescribed

There are many advantages to using T3 to optimize our metabolic rate. T3 will also increase your bodys ability to synthesize protein.  It is often the last thing added into a precontest bodybuilding diet, as it has a reputation for getting rid of the last few percentages of  bodyfat & the “sticky fat” as its called in bodybuilding.

Most of the thyroid hormone circulating in the blood is bound to transport proteins. Only a very small fraction of the circulating hormone is free (unbound) and biologically active, hence measuring concentrations of free thyroid hormones is of great diagnostic value.

When thyroid hormone is bound, it is not active, so the amount of free T3/T4 is what is important. For this reason, measuring total thyroxine in the blood can be misleading.

Thyroxine and triiodothyronine can be measured as free thyroxine and free triiodothyronine, which are indicators of thyroxine and triiodothyronine activities in the body. They can also be measured as total thyroxine and total triiodothyronine, which also depend on the thyroxine and triiodothyronine that is bound to thyroxine-bindingglobulin. A related parameter is the free thyroxine index, which is total thyroxine multiplied by thyroid hormone uptake, which, in turn, is a measure of the unbound thyroxine-binding globulins

Today most patients are treated with levothyroxine, or a similar synthetic thyroid hormone.  However, natural thyroid hormone supplements from the dried thyroids of animals are still available. Natural thyroid hormones have become less popular, mostly due to rumors that varying hormone concentrations in the thyroids of animals before they are slaughtered leads to inconsistent potency and stability.  However natural products mix thyroid powder from multiple lots and perform analytical tests to insure strict compliance with FDA standards, and it has actually been the synthetic thyroid hormone that has shown a consistent history of potency or stability problems.  Levothyroxine contains T4 only and is therefore largely ineffective for patients unable to convert T4 to T3.  These patients may choose to take natural thyroid hormone as it contains a mixture of T4 and T3, or alternatively supplement with a synthetic T3 treatment.  Some natural thyroid hormone brands are F.D.A. approved, but some are not. Thyroid hormones are generally well tolerated.  Thyroid hormones are usually not dangerous for pregnant women or nursing mothers, but should be given under a doctor’s supervision. In fact, if a woman who is hypothyroid is left untreated, her baby is at a higher risk for birth defects. When pregnant, a woman with a low functioning thyroid will also need to increase her dosage of thyroid hormone.  One exception is that thyroid hormones may aggravate heart conditions, especially in older patients; therefore, doctors may start these patients on a lower dose & work up to avoid risk of heart attack

Cabergoline Uses

There are many questions regarding Dostinex.  Cabergoline is often marketed as Dostinex.  Dostinex is a medication that also goes by the name Cabaser. Originally, cabergoline aka Dostinex was created to treat pituitary tumors by lowering the levels of prolactin in the body.  However other uses have been found for Dostinex as well. As with any drug, ask your doctor to make sure it is safe and will not interact with other medications you’re taking.

 

Read more about the uses of Cabergoline on a blog that is specifically regarding cabergoline and Dostinex or Cabaser here: Cabergoline Uses

Dopamine

dostinex research chemicals


Dopamine

Dopamine was first synthesized in 1910 by George Barger and James Ewens at Wellcome Laboratories in London, England.  Dopamine is a catecholamine neurotransmitter present in a wide variety of animals, including both vertebrates and invertebrates.  Dopamine is a neurotransmitter, one of those chemicals that is responsible for transmitting signals in between the nerve cells (neurons) of the brain. Very few neurons actually make dopamine.  Some, in a part of the brain called the substantia nigra, are the cells that die during Parkinsons disease. The functions of  Dopamine others, located in a part of the brain called the ventral tegmental area (VTA), are less well defined and are the major source of the aforementioned controversy (and the focus of this post). When dopamine neurons become activated, they release dopamine.In the brain, this substituted phenethylamine functions as a neurotransmitter, activating the five known types of dopamine receptors—D1, D2,D3, D4, and D5—and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area.  Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary.

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Dopamine is available as an intravenous medication acting on the sympathetic nervous system, producing effects such as increased heart rate and blood pressure. However, because dopamine cannot cross the blood-brain barrier, dopamine given as a drug does not directly affect the central nervous system. To increase the amount of dopamine in the brains of patients with diseases such as Parkinson’s disease and dopa-responsive dystonia, L-DOPA  is often given because it crosses the blood-brain barrier relatively easily.

Dopamine reduces the influence of the indirect pathway while increasing the actions of the direct pathway within the basal ganglia.  Insufficient dopamine biosynthesis in the dopaminergic neurons can cause Parkinson’s disease, a condition in which one loses the ability to execute smooth, controlled movements.  Many experimental drugs for Parkinson’s disease revolve around Dopamine.  Cabergoline aka Dostinex directly affects the brain and Dopamine.

Dopamine is the primary neuroendocrine inhibitor of the secretion of prolactin from the anterior pituitary gland.  Dopamine produced by neurons in the arcuate nucleus of the hypothalamus is secreted into the hypothalamo-hypophysial blood vessels of the median eminence, which supply the pituitary gland. The lactotrope cells that produce prolactin, in the absence of dopamine, secrete prolactin continuously; dopamine inhibits this secretion. Thus, in the context of regulating prolactin secretion, dopamine is occasionally called prolactin-inhibiting factor (PIF), prolactin-inhibiting hormone (PIH), or prolactostatin.

Cabergoline

Cabergoline which is commonly known as Cabaser or Dostinex, an ergot derivative, is a potent dopamine receptor agonist on D2 receptors. Studies show cabergoline has a direct inhibitory effect on prolactin. It is frequently used as a first-line agent in the management of prolactinomas due to higher affinity for D2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine.  Cabergoline is a commonly studied research chemical.  Research chemicals are available to individuals for research purposes.  Research chemicals like cabergoline can be found under many names.  For example the research chemical cabergoline is also listed under Dostinex.

Cabergoline, Dostinex, Dopamine to be continued…

Deprenyl, Selepryl, Selegilene As A Performance Enhancer


Deprenyl / Selegiline / Selepryl

Selegiline aka Deprenyl or Selepryl (depending on the brand of Selegiline) is commonly used for research and sold as a research chemical.  It also has approved uses as a prescription drug in the United States for Parkinson’s disease, ADHD, and Alzheirmer’s.  Prior to being a regulated substance Selegiline aka Deprenyl was very popular in track and field because users reported it seemed to boost reaction time and those athletes can win or lose a sprint by simply reacting more quickly to the starting gun.**  Deprenyl has also been reported to improve contractile ability of muscles due to its ability to improve neuron firing.  If the above information is accurate, Deprenyl may have potential as a strength / speed enhancer.  Since testing of it several years ago wasn’t prevalent, the use of Deprenyl as a performance enhancer was very popular.  Selegiline is not approved for these uses in the USA.

research chemicals

**For bodybuilders it’s marginally useful because Deprenyl helps well-being. For strength /speed athletes it could potentially boost their learning ability when it comes to new skills, improve reaction time, and help them be more efficient.

We had one reader report that he used Deprenyl as Selegilene during PCT many years ago.  He said Deprenyl helped him learn new skills for a sport more quickly and improved his reaction time. He had been using 5mgs/day of Deprenyl / Selegilene and found that to be a decent dose.  Since then the use of Selegiline has been regulated and is no longer available for human consumption unless prescribed by a doctor.

Selegilene is used in the treatment of alzheimers.  Selegilene is also starting to be used as a treatment for ADHD.

DEPRENYL is the first proven anti-aging, life extension drug. A discovery of major importance in preventive medicine.” -Dr. Ronald Klatz.

Beware that deprenyl can cause a false positive for methamphetamine during standard drug-testing..

**Let’s face it, drugs work.  They improve muscle mass, strength, and athletic performance.  But for many reasons drug use by athletes (or anyone) is a serious problem.  Not only are there moral and health ramifications to the use of performance-enhancing drugs by athletes, but for substances such as the illicit drugs, the amphetamines, anabolic steroids and growth hormone we also have to consider the legal consequences of their use.  Growth hormone and anabolic steroids, drugs used mainly by athletes, have been classified as controlled substances in North America and other places.

In addition to the legal ramifications of growth hormone and anabolic steroid use, there are the health risks inherent in how these compounds are obtained and used.  Think of the main source of these drugs.  People run the risk of getting counterfeit drugs that may be tainted with who knows what and putting themselves at further risk.

If you are an athlete and you are considering using performance enhancing drugs you must consider the legal, moral and health ramifications.  In light of the above I encourage you to look to safe and natural alternatives.  A solid nutritional supplementation tied with a healthy diet and proper training is a viable alternative.

 If and only if you are looking to buy Deprenyl or Selegiline for research purposes you can buy Selegiline here: Buy Selegiline

Research Chemicals Brain Health

Health Tip: Aerobics Goes Brainal: Neurobics

research chemicals

Health: Let’s juice up that brain of yours. American researchers coined the term ‘neurobics’ for tasks which activate the brain’s own biochemical pathways and to bring new pathways online that can help to strengthen or preserve brain circuits. Increase your mental health. Brush your teeth with your ‘other’ hand, take a new route to work or choose your clothes based on sense of touch rather than sight. People with mental agility tend to have lower rates of Alzheimer’s disease and age-related mental decline.  A new take on health!  You will probably be hearing the term neurobics more often in the future.  Neurobics should become common place.  There are already many apps for tablets and phones that promote brain excersise.

Personally I started brushing my teeth with my left hand to improve my hand coordination.  I am primarily right-handed.  Improve your health and your coordination. Try it out!

Look for more interesting health related tips from our research chemicals blog.

New Extreme Weight Loss Surgery Is Questionable

Extreme surgery for weight loss involves removing up to 80 per cent of a person’s stomach has doctors divided.

fast weight loss

Not An Actual Subject

Some Doctors say it is so risky they will not even perform the surgery while others say patients can lose 60-80lbs in a year and can still eat carbs like bread and pasta.

The operation called sleeve gastrectomy – or “sleeving” – can result in serious complications and is 10Xs more dangerous than lap-banding.

Once the outer part of the stomach is completely removed via keyhole technique, the remaining piece of the stomach is stapled to form a banana-shaped tube. This reduces its holding capacity from about 2 litres to 100mL, increasing stomach pressure after eating small portions to make people feel full quicker.

One of Australia’s “sleeving” pioneers, Dr Michael Talbot, said the most serious complication from the surgery is gastric fluid leaking from the staple line causing serious infection that could result in a month-long hospital stay or even death.

Lap-banding is safer.  Dr Talbot warned that sleeving should only be performed on the morbidly obese in need of rapid weight loss.

“That risk varies from 0.5 per cent to 3 per cent depending on the centre where the surgery is occurring and the experience of the surgeon,” said Dr Talbot, an upper gastro intestinal surgeon at St George Public and Private Hospitals.

Patients average loss is near 60% of their extra weight!

Dr Talbot said on average, patients lose 60% of the extra weight they carry 12 months.

Dr Ali Zarrouk, who performed the first sleeve gastrectomy at Campbelltown Private Hospital in September, said patients who have a sleeve gastrectomy lose weight immediately and don’t have to avoid pasta, bread or meat.

Single mother Sharon Fairbairn weighed 105kg and struggled to run after her seven-year-old daughter, Anabella, when she had the radical operation in September last year. “I wish I’d done it 10 years ago,” she said.

After Medicare cover, out-of-pocket expenses range between $3000 and $7000 for the procedure.

However surgeon and associate professor at the Centre for Obesity Research and Education Wendy Brown refuses to perform sleeve gastrectomies as the surgery is too risky.

“With a (gastric) band or even a (gastric) bypass you can actually do another operation if you find out you’ve done it wrong, but with a sleeve gastrectomy you’ve taken a patient’s stomach out,” she said. “They can’t grow another stomach.”

This is an extreme measure to take for weight loss and should only be considered after all other options are exhausted.  The easiest way to get slim is to not let yourself get heavy.  Of course that is not practical all the time.  We have studied research chemicals such as Clenbuterol, T3, Rimonabant, Albuterol and ECA stacks and have had great results.

Good luck on your quest to lose weight fast.  Well most of us prefer to lose weight fast vs slow…

Cabergoline Known As Dostinex

Cabergoline is branded as Dostinex.  DOSTINEX comes in the form of tablets. Dostinex Tablets contain cabergoline, a dopamine receptor agonist. The chemical name for is is 1-[(6-allylergolin-8ß-yl)-carbonyl]-1-[3-(dimethylamino) propyl]-3-ethylurea. The empirical formula for cabergoline is C26H37N5O2, and the molecular weight of is is 451.62. The structural formula for cabergoline aka Dostinex is as follows:

DOSTINEX® (cabergoline) Structural Formula Illustration

Cabergoline is a white powder soluble in ethyl alcohol, chloroform, and N, Ndimethylformamide (DMF); slightly soluble in 0.1N hydrochloric acid; very slightly soluble in n-hexane; and insoluble in water.

DOSTINEX  Tablets, for oral administration, contain 0.5 mg of cabergoline. Dostinex inactive ingredients consist of leucine, USP, and lactose, NF.

What are some precautions when taking cabergoline (Dostinex)?

Before taking Dostinex, tell your doctor or pharmacist if you are allergic to this medication; or to other ergot medications (such as ergotamine); or if you have any other allergies. Dostinex may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using Dostinex, tell your doctor or pharmacist your medical history, especially of: liver disease, high blood pressure (hypertension), heart valve disease, abnormal scarring/thickening of the lining in the lungs/heart/behind the abdomen (pulmonary/pericardial/retroperitoneal fibrosis).

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.

Excretion

After oral dosing of radioactive Cabergoline to five healthy volunteers, approximately 22% and 60% of the dose was excreted within 20 days in the urine and feces, respectively. Less than 4% of the dose was excreted unchanged in the urine. Nonrenal and renal clearances for Cabergoline are about 3.2 L/min and 0.08 L/min, respectively. Urinary excretion in hyperprolactinemic patients was similar.

Click here to buy cabergoline from a reputable research chemical distributor.

Serm Vs Aromatase Inhibitor (AI)

 Aromatase Inhibitor (AI): Aromatase inhibitors exhibit a very different mechanism of action than SERM’s. Aromatase inhibitors prohibit the conversion of androgens into estrogen in muscle, fat, breast, and brain. ex: Anastrazole aka Arimidex and FEMARA aka letrozole tablets.

(SERM) Compounds that bind with estrogen receptors and exhibit estrogen action in some tissues and anti-estrogen action in other tissues. The ideal SERM would deliver all of the benefits of estrogen minus the side effects.  F0r example: Clomiphene Citrate aka Clomid or Serophene and Tamoxifen aka Nolvadex.

NOTE: Clomid and Nolvadex are both anti-estrogens belonging to the same group of triphenylethylene compounds. They are structurally related and specifically classified as selective estrogen receptor modulators (SERMs) with mixed agonistic and antagonistic properties. This means that in certain tissues they can block the effects of estrogen, by altering the binding capacity of the receptor, while in others they can act as actual estrogens, activating the receptor. In men, both of these drugs act as anti-estrogens in their capacity to oppose the negative feedback of estrogens on the hypothalamus and stimulate the heightened release of GnRH (Gonadotropin Releasing Hormone). LH output by the pituitary will be increased as a result, which in turn can increase the level of testosterone by the testes.

Although these two are related anti-estrogens, they appear to act very differently at different sites of action. Nolvadex seems to be strongly anti-estrogenic at both the hypothalamus and pituitary, which is in contrast to Clomid, which although a strong anti-estrogen at the hypothalamus, seems to exhibit weak estrogenic activity at the pituitary. Selective Estrogen Receptor Modulator 

Research Chemicals USClomid Nolvadex

Cabergoline – The Latest In Libido Enhancement

Cabergoline has been described as being able to do everything that Viagra can’t! Libido Booster!

libido

Libido Enhancer: Cabergoline aka Dostinex increases the levels of dopamine through its action of stimulating D2 receptor sites. Cabergoline is officially approved to assist in the treatment of Parkinson’s disease, as well as treat states of prolactinoma i.e. prevent breast development in men and reduce excess milk secretion in women.

However, cabergoline (brand name Dostinex) has been described as being able to do everything that Viagra can’t! This is because rather than induce an erection (asViagra can); cabergoline has been shown to improve libido, orgasm and ejaculation (which Viagra has not).

dostinex libido

Cabergoline is from the dopaminergic family of drugs that increase the level of dopamine and also decreases the levels of the hormone prolactin. Prolactin is the hormone secreted in women after giving birth and to enhance their lactation for breast feeding. However, prolactin has recently been shown to be an inhibitor to a healthy libido, this may help explain why many women have a low sex drive after giving birth- whilst they are breast feeding. But men can also suffer from prolactinoma (high levels of prolactin) leading to a lack of sex drive- as well as developing breasts, particularly as prolactin levels tend to increase for most men with age.

enhance libido

Recently it was discovered that prolactin is released immediately after an ejaculation and may be part of the reason men like to go sleep after sex with no will for further love making.  That is no fun!

Cabergoline has been proven to significantly decrease prolactin and in so doing increase the sex drive (libido) substantially. There have been reports of enhanced and multiple orgasms as well as stronger ejaculations.  These are all positives in our books.  Many males could benefit from Cabergoline and could possibly impress their significant others.  Cabergoline aka Dostinex should be more popular than viagra.

So now what?  I am going to try some Cabergoline!

Research Chemicals

research chemicals

Research chemicals (RC) is actually a name administered to a deep range of psychoactive drugs that are implicitly sold for use in scientific and healing investigation. Countless Research chemicals are actually structurally identical to scheduled chemicals, and could certainly be actually considered to be actually analogs. Even with the evident analogy by having scheduled compounds, analysis chemicals tumble into a legal gray location under U.S. law. Because the chemicals are industried for legitimate purposes (i.e. not for human consumption), their possession and distribution accomplishes not essentially contravene the Analog Act.
Research chemicals have not been via scientific testings and are therefore not accepted as protected for human consumption. The short as well as
long-term safety profiles of their usage are not well established in many situations. An amount of medicines without psychoactive ramifications, consisting of synthetic anabolic steroids, as well as by-products of erectile dysfunction treatments sildenafil aka Viagra and Tadalafil aka Cialis, have definitely also been actually marketed as research chemicals for similar legal reasons.
One collection of Research Chemicals are actually simply chemicals that are based on preferred substances nonetheless their molecular structure has actually been just a little altered to make the chemical legal. These legal research chemicals are actually classified as ‘analogs’ or ‘derivatives’.
For Example:
Over the last few of years the search for finding a legal substitute for MDMA has resulted in a research chemicals market that has actually been flooded with exotic compounds such as mephedrone, methoxetamine, 5-APB, Benzo-Fury (6-APB), methylone, butylone and lots of several more odd compounds. The super fast advancement of these compounds make it inconceivable for legislators to keep up with the market and as a result it generally takes a while until they ‘re banned.
The research chemicals “drugs” are actually being sold as soak sodiums, tree food, or plant fertilizer and usually industried with the terms “not for human consumption” under item labels providing Ivory Influx, Vanilla Sky, Pure Ivory, as well as Sextacy to circumvent FDA precept and to shield their quasi legal standing.

Viagra – What Is Viagra?

Sildenafil citrate, offered as Viagra, Revatio and under numerous more trade names, is a drug made for treatment of erectile dysfunction as well as pulmonary arterial hypertension (PAH). Sildenafil Viagra was actually developed by British scientists and then brought to market by the US-based pharmaceutical company Pfizer. Sildendafil viagra appears by inhibiting cGMP-specific phosphodiesterase type 5, a molecule that delays degradation of cGMP, which regulates vital fluid flow in the penis. Since turning into available in 1998, sildenafil viagra has been the prime treatment for erectile dysfunction; its most important competitors on the market are tadalafil (Cialis) and vardenafil (Levitra).

Sexual dysfunction
The main use of sildenafil viagra is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Sildenafil viagra main use is now standard treatment for erectile dysfunction in all settings, including diabetes. Viagra has similar functions to Cialis but with quicker and shorter results.
People on antidepressants may experience sexual dysfunction, either as a result of their illness or as a result of their treatment. A 2003 study showed that sildenafil improved sexual function in men in this situation. Following up to earlier reports from 1999, the same researchers found that sildenafil was able to improve sexual function in female patients on antidepressants as well.
Pulmonary hypertension
As well as erectile dysfunction, sildenafil citrate is also effective in the rare disease pulmonary arterial hypertension (PAH). It relaxes the arterial wall, leading to decreased pulmonary arterial resistance and pressure. This, in turn, reduces the workload of the right ventricle of the heart and improves symptoms of right-sided heart failure. Because PDE-5 is primarily distributed within the arterial wall smooth muscle of the lungs and penis, sildenafil acts selectively in both these areas without inducing vasodilation in other areas of the body. Pfizer submitted an additional registration for sildenafil to the FDA, and sildenafil was approved for this indication in June 2005. The preparation is named Revatio, to avoid confusion with Viagra, and the 20-milligram tablets are white and round. Sildenafil joins bosentan and prostacyclin-based therapies for this condition.
Altitude sickness
Sildenafil also useful for the prevention and treatment of high-altitude pulmonary edema associated with altitude sickness such as that suffered by mountain climbers. Sildenafil is becoming an accepted treatment for this condition, in particular in situations where the standard treatment of rapid descent has been delayed for some reason.
Dosage

Viagra
Sildenafil– Viagra pills are blue and diamond-shaped with the word “Pfizer” engraved on one side, and “VGR xx” (where xx stands for “25?, “50? or “100?, the dose Viagra in milligrams) engraved on the other. The dose of sildenafil– viagra for erectile dysfunction is 25 mg to 100 mg taken not more than once per day between 30 minutes and 4 hours prior to sexual intercourse.
The dosage for PAH pulmonary arterial hypertension (Revatio) is one 20 mg tablet three times a day. Revatio pills are white, round, film-coated tablets imprinted with “RVT 20? embossed on one side.

Clenbuterol A Little Info

Clenbuterol

clenbuterol

Clenbuterol is a bronchodilator that is used in many parts of the world. Clenbuterol is distributed in 20 mcg tablets.  Clenbuterol also comes as a syrup, and injections. Clenbuterol is classified as a sympathomimetics. Clenbuterol affects the sympathetic nervous system in many ways. They are mediated by the distribution of adrenoceptors. The body has nine types of receptors that are classified by alpha or beta. They are subcategorized by type number.

Clenbuterol is frequently used to treat asthma. Clenbuterol is also used to treat hypertension, cardiovascular shock, arrhythmias, migraine headaches, and anaphylactic shock. Clenbuterol is also frequently used as a performance enhancing drug.  Clenbuterol is known for its ability to promote rapid weight loss.  Clenbuterol can help you lose weight but keep your muscle.

Visit Research Chemicals for more info on Clenbuterol soon.

Sildenafil aka Viagra

Viagra – Sildenafil Citrate

Sildenafil citrate, sold as ViagraRevatio and under various other trade names, is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). It was originally developed by British scientists and then brought to market by the US-based pharmaceutical company Pfizer.  It acts by inhibiting cGMP-specific phosphodiesterase type 5, an enzyme that delays degradation of cGMP, which regulates blood flow in the penis. Since becoming available in 1998, sildenafil has been the prime treatment for erectile dysfunction; its primary competitors on the market are tadalafil (Cialis) and vardenafil (Levitra).

Sexual dysfunction

The main use of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction in all settings, including diabetes.  It has similar functions to Cialis but with quicker but shorter results.

People on antidepressants may experience sexual dysfunction, either as a result of their illness or as a result of their treatment. A 2003 study showed that sildenafil improved sexual function in men in this situation.  Following up to earlier reports from 1999, the same researchers found that sildenafil was able to improve sexual function in female patients on antidepressants as well.

Pulmonary hypertension

As well as erectile dysfunction, sildenafil citrate is also effective in the rare disease pulmonary arterial hypertension (PAH). It relaxes the arterial wall, leading to decreased pulmonary arterial resistance and pressure. This, in turn, reduces the workload of the right ventricle of the heart and improves symptoms of right-sided heart failure. Because PDE-5 is primarily distributed within the arterial wall smooth muscle of the lungs and penis, sildenafil acts selectively in both these areas without inducing vasodilation in other areas of the body. Pfizer submitted an additional registration for sildenafil to the FDA, and sildenafil was approved for this indication in June 2005. The preparation is named Revatio, to avoid confusion with Viagra, and the 20-milligram tablets are white and round. Sildenafil joins bosentan and prostacyclin-based therapies for this condition.

Altitude sickness

Sildenafil also useful for the prevention and treatment of high-altitude pulmonary edema associated with altitude sickness such as that suffered by mountain climbers.  Sildenafil is becoming an accepted treatment for this condition, in particular in situations where the standard treatment of rapid descent has been delayed for some reason.  

Dosage

Viagra

Sildenafil – Viagra pills are blue and diamond-shaped with the word “Pfizer” engraved on one side, and “VGR xx” (where xx stands for “25″, “50″ or “100″, the dose Viagra in milligrams) engraved on the other. The dose of sildenafil – viagra for erectile dysfunction is 25 mg to 100 mg taken not more than once per day between 30 minutes and 4 hours prior to sexual intercourse.

The dosage for PAH pulmonary arterial hypertension (Revatio) is one 20 mg tablet three times a day. Revatio pills are white, round, film-coated tablets imprinted with “RVT 20″ embossed on one side.

Tadalafil aka Cialis Info

 

Tadalafil  is most commonly known as Cialis.  Tadalafil is a PDE5 inhibitor, currently marketed in pill form for treating erectile dysfunction (ED) under the name Cialis; and under the name Adcirca for the treatment of pulmonary arterial hypertension. It initially was developed by the biotechnology company ICOS.   Shorltly thereafter Tadalafil was developed and marketed world-wide by Lilly ICOS, LLC, .  Tadalafil or Cialis generally comes in liquid form from research chemical sites.  If you have a prescription you can buy Cialis tablets, in Cialis 5 mg, Cialis 10 mg, and Cialis 20 mg doses, which are yellow, film-coated, and almond-shaped. The approved tadalafil dose for pulmonary arterial hypertension is 40 mg (two 20-mg  Cialis tablets) once daily.

Tadalafil is also manufactured and sold under the name of Tadacip by the Indian Pharmaceutical company Cipla in doses of 10 mg and 20 mg.

On November 21, 2003 the Food and Drug Administration approved tadalafil as Cialis for sale in the United States as the third ED prescription drug pill after sildenafil citrate aka Viagra and vardenafil aka Levitra. Cialis’s 36-hour effectiveness earned it the nickname, “The Weekend Pill”; like sildenafil Viagra and vardenafil Levitra, tadalafil Cialis is recommended as an ‘as needed’ medication. Cialis is the only one of the three that is also offered as a once-daily medication.

Moreover, tadalafil was approved in May 2009 in the United States for the treatment of pulmonary arterial hypertension and is currently under regulatory review in other regions for this condition. In late November 2008, Eli Lilly sold the exclusive rights to commercialize tadalafil for pulmonary arterial hypertension in the United States to United Therapeutics for an upfront payment of $150 million.

Many Chemical Research companies provide Cialis and Viagra for study.

Research Chemicals History

History of Research Chemicals

research chemicals

The term research chemical became popular during the 1990s.  Research chemicals became prevalent due to a number of online vendors purporting to sell a variety of psychoactive chemicals (many of which were analogues of scheduled chemicals) for legitimate research purposes. Research chemical vendors believed that this marketing strategy would allow them to avoid prosecution under the Federal Analog Act, which is an amendment to the U.S. Controlled Substances Act (effective 1986). Under this legislation, any chemical which is functionally and structurally ‘substantially similar’ to a Schedule I or II controlled substance can also be treated as scheduled, but only if the prosecutor can demonstrate intent for human consumption.  Vendors use disclaimers to legally sell research chemicals.The term research chemicals is distinct from the more antiquated phrase ‘designer drug’. Research chemicals may be clearly identifiable as analogues of scheduled chemicals such as Viagra or Cialis, but remain in a legal grey area (under U.S. law at least) due to the difficulties in proving intent for consumption. ‘Designer drugs’ on the other hand are chemicals which have been synthesized with the intention of circumventing more specific scheduling laws and are targeting users for consumption.

Research Chemicals – What Are Research Chemicals?

What Are Research Chemicals? 

research chemicals

Research chemical (RC) is a term applied to a broad variety of psychoactive drugs that are implicitly sold for use in scientific and medical research. Many research chemicals are structurally similar to scheduled chemicals, and could be considered to be analogues. Despite the evident analogy with scheduled compounds, research chemicals fall into a legal grey area under U.S. law. Since the chemicals are marketed for legitimate purposes (i.e. not for human consumption), their possession and distribution does not necessarily contravene the Analog Act.

Research chemicals have not been through clinical trials and are therefore not approved as safe for human consumption. The short and
long-term safety profiles of their use are not well established in most cases. A number of drugs without psychoactive effects, including synthetic anabolic steroids, and derivatives of erectile dysfunction medications sildenafil aka Viagra and Tadalafil aka Cialis, have also been marketed as research chemicals for similar legal reasons.

One group of Research Chemicals are simply chemicals that are based on popular substances however their molecular structure has been slightly changed to make the chemical legal.  These legal research chemicals are classified as ‘analogues’ or ‘derivatives’ .

For Example:

Over the last couple of years the quest for finding a legal substitute for MDMA has resulted in a research chemicals market that has been flooded with exotic compounds such as mephedrone, methoxetamine, 5-APB, Benzo-Fury (6-APB), methylone, butylone and many many other strange compounds. The rapid development of these compounds make it impossible for legislators to keep up with the market and therefore it usually takes a while before they’re banned.

The research chemicals “drugs” are being sold as bath salts, plant food, or plant fertilizer and typically marketed with the words “not for human consumption” under product names including Ivory Wave, Vanilla Sky, Pure Ivory, and Sextacy to circumvent FDA regulation and to safeguard their quasi legal status.